berberine active contains phellodendron used traditionally to support healthy liver and bowel function.* the compounds in phellodendron are used traditionally in chinese herbal preparations to: promote regularity of bowel function* support a healthy bowel environment* support healthy liver function* act as a general tonic herb* provide antioxidant activity* berberine active is standardized to contain two hundred mg of berberine, the main active constituent of phellodendron which is an alkaloid of the isoquinoline group to ensure optimal strength and quality. about phellodendron ( phellodendron amurense) phellodendron bark has been traditionally used to cleanse the lower gastrointestinal tract. cleansing and promoting health in the lower gastrointestinal tract encourages a healthy gastrointestinal environment. phellodendron has also been used traditionally to support healthy liver function.* suggested use: one tablet two - four times daily, or as directed. caution: not to be used during pregnancy and lactation unless otherwise directed by a qualified health care professional. for other contraindications and cautions consult your health care professional. this product is packaged in a facility that manufactures other products containing soy, milk, egg, wheat, peanut, tree nuts, fish and shellfish. keep out of reach of children. store in a cool, dry place out of direct sunlight. nutrients & ingredients each serving size (one tablet) contains: c@lcium twenty-six mg, phellodendron twenty:one extract four hundred and forty mg (from phellodendron amurense stem bark eight.eight g, containing berberine two hundred mg). other ingredients: microcrystalline cellulose, sodium starch glycolate, croscarmellose sodium, hypromellose, magnesium stearate, dibasic c@lcium phosphate dihydrate and silicon dioxide.