Comprehensive microbiome support with prebiotics, probiotics, postbiotics and digestive enzymes. 
Custom-formulated blend of patented pre-, pro-, and postbioticsClinically proven to 
enhance gut barrier functionSupports digestion and gut health by promoting a healthy microbiome and balanced floraBacillus probiotic species supports immune functionPreforPro® prebiotics amplify effectiveness of probiotics and reduces symptoms related to GI inflammationFormulated with 0.5 billion CFU live Bacillus organisms CoreBiome® Tributryin postbiotic to support healthy inflammatory response and stimulate cell renewal - 
this nutrient can have a strong odor when taken out of the bottle.
KEY INGREDIENTS
GutHealth biotic blend: 550mg
Prebiotics: PreforPro® (LHO1 Myoviridae, LL5 Siphoviridae, T4D Myoviridae, LL12 Myoviridae)
Probiotics: (0.5 billion CFU) Bacillus subtilis, Bacillus coagulans, Bacillus clausii
Postbiotics: CoreBiome® (standardized to 55% Tributyrin) - 
this nutrient can have a strong odor when taken out of the bottle
Enzyme blend:
 Protease blend (protease I, II, III, IV, V, DPP-IV), amylase I, amylase
 II, Lipase, Lactase, Hemicellulase, Beta-Glucanase, Xylanase, 
Pectinase, Cellulase, Mannanase, Alpha-Galactosidase, Gluco-amylase, 
Diastase, Invertase, Bromelain, Serrapeptase, (Peptizyme SP), Papain
Why take Gut Health 4-in-1?
This
 unique blend of prebiotics, probiotics, and tributyrin is clinically 
proven to enhance microbiome health and gut barrier function. 
The gut is home to an 
estimated 70% of the body’s immune cells. Intestinal microbiome helps regulate many bodily systems including the brain, heart, bone, muscle, and skin. 
Probiotic
 supplementation can improve microbial balance, stimulate host immunity,
 support the intestinal barrier that protects the body from pathogens, 
and reduce the risk of intestinal diseases. 
Those with 
MTHFR genetic mutations are at greater risk of hyperhomocysteinemia (HHcy). HHcy has been associated with gut inflammation 
and other gastrointestinal disorders, including higher risk of inflammatory bowel disease (IBD).
 Gluten intolerance is another cause of gut inflammation and intestinal permeability.
Gut
 Health 4-in-1 is designed to support gut health and to assist in the 
breakdown of macro- and micronutrients, which may improve absorption of 
B-vitamins and mitigate gastrointestinal disorders.
 
Why Bacillus probiotics?
Unlike other probiotics, spore-based probiotics are resistant to gastric acid. This allows them to 
pass through the stomach and enter the intestine in the same concentration without being degraded.
In
 addition, Bacillus strains are shown to prevent the colonization of 
pathogenic bacteria that compete for nutrients and adhesion receptors. 
B.
 subtilis and B. coagulans were found to improve absorption of nutrients
 by stimulating the growth of beneficial bacteria and producing a 
healthier intestinal system.
Gut
 Health 4 in 1 contains clinically researched and patented prebiotics, 
probiotics, and postbiotics along with a comprehensive blend of 
digestive enzymes to promote digestion, ease digestive discomfort and 
promote nutrient absorption. 
Why PreforPro®?
PreforPro®
 is a prebiotic bacteriophage blend shown to accelerate growth of a 
broad spectrum of probiotic species including Bifidobacterium, 
Lactobacillus, and Bacillus subtilis.
Phages
 can reduce populations of ‘bad’ bacteria, allowing more space for 
healthy bacteria (probiotics) to proliferate. When used in combination 
with probiotics, 
PreforPro®
 is shown to enhance probiotic effects, reduce GI inflammation and colon
 pain, increase Lactobacillus and short-chain fatty acid-producing 
microbes in the gut.
As PreforPro® is not fiber or starch-based, it doesn’t cause digestive discomfort, bloating, or flatulence.
Why Corebiome®?
CoreBiome® is the number one selling tributyrin in the world. This 
unique derivative of butyrate is a short-chain fatty acid (SCFA) 
produced by healthy bacteria in the gut. Butyrate is the primary   
source for the cells of our gut lining and plays a key role in digestive
 health and immune function. By delivering CoreBiome® directly to both 
the small and large intestine, this valuable SCFA supports cells 
involved in immune health. 
CoreBiome® is also the first SCFA clinically shown to boost butyrate and stimulate butyrate-producing bacteria. 
Tributyrin
 supplementation is shown to preserve immune responses, reduce oxidative
 stress in the colon and maintain integrity of intestinal villi 
vasculature.
Why digestive enzymes?
Digestive enzymes assist in the breakdown of proteins, carbohydrates, lipids, gluten, and dairy. Supplementation may 
help in the management of digestive and/or malabsorption disorders including lactose intolerance and gluten sensitivity.