methyl life L-Methylfolate 15 Mg 90 Chewable Tablets

Therapeutic high-dose of bioactive L-methylfolate uniquely formulated with the internationally-patented Magnafolate® PRO, active vitamin B12, and inositol to naturally support healthy mood, cognitive function, methylation and homocysteine support. L-methylfolate is the predominant form of folate circulating in the body and used for biological processes1. Studies show *15mg methylfolate + SSRI to be the most effective dose for improving depressive symptoms2. Methylfolate is the biologically activated form of folate and the only form that can cross the blood-brain barrier3. Support for brain function4Supports cardiovascular health5Support for healthy immune function6Supports nerve function7 and healthy myelin formation22Nervous system maintenance21Support for preconception, pregnancy, and fetal health8Involved in reducing20 and maintaining healthy homocysteine levels9Essential nutrient required for optimal DNA methylation19 and neurotransmitter synthesis10Adjunctive support for serotonin selective reuptake inhibitors23Suitable for people with MTHFR mutations11 Product details (30 capsule servings per container)
Key ingredients:   Folate - 15,000 mcg (as L-5-Methyltetrahydrofolate, Calcium - Magnafolate® PRO)Vitamin B12 - 1,000 mcg (as Hydroxocobalamin)Inositol - 180 mg Methylfolate 15mg+ Enhance Mood is a highly bioactive form of folate made with the purest methylfolate available12.  Maximum absorption and bioavailabilityNo prescription required Available in 2.5mg, 3mg+B12, 5mg, 7.5mg+B12, 10mg, 15mg, 15mg+B12 Rigorously tested for consistency, purity, safety, and potencyAbsolutely no fillers or additives of any kind Why take Methylfolate 15mg+ Enhance Mood? Synthesis of mood-enhancing neurotransmitters (serotonin, dopamine, and norepinephrine) is regulated by L-methylfolate, a derivative of folate10. Methylfolate has demonstrated efficacy as an adjunctive treatment for individuals who have not responded optimally to antidepressant therapy2. Supplementing with 15mg methylfolate alongside SSRIs may be effective in improving symptoms of depression25. Methylfolate is absorbed more efficiently than synthetic folicacid which must be converted to active folate by the enzyme methylenetetrahydrofolate reductase (MTHFR)13. Hydroxocobalamin works closely alongside folate in converting homocysteine to methionine to support mood and nervous system health. Individuals with MTHFR mutations may raise their nutrient status more efficiently with methylfolate11 and hydroxocobalamin26. Inositol may be effective in treating disorders responsive to selective serotonin reuptake inhibitors, including depression, panic disorders, and obsessive-compulsive disorder24. Methylfolate 15mg+ Enhance Mood is 100% free from all fillers and additives. Who is affected by MTHFR mutations? The MTHFR mutation is much more common than many people realize (it’s estimated around 50% of the global population have at least 1 of 2 common variants).  Approximately 25% of the global population are carriers of the MTHFR mutation C677T, with Hispanics making up the highest proportion (47%), East Asians (30%), South Asians (12%) and Africans (9%).  Another 25% of the global population have the MTHFR mutation A1298C, which is highest in South East Asians (42%) and Europeans (31%). The frequency of the 1298A>C polymorphism in Hispanics and Africans is 15%14.  An increasing number of studies have shown links between those with MTHFR polymorphisms and an increased risk for high levels of homocysteine, depression, and reduced antidepressant effectiveness15.  MTHFR is also linked to elevated homocysteine levels, which can cause serious vascular diseases, dementia, infertility, and other chronic illnesses16. For these people, L-methylfolate supplementation is shown to be the most effective way to provide this form of folate10.  Methyl-Life’s® Methylfolate is an active form of folate that can bypass the MTHFR mutation. It is already in its metabolized form, which means it can be readily absorbed and utilized in the body for many biochemical reactions. Why Magnafolate® PRO? Methyl-Life’s® Methylfolate 15mg+ Enhance Mood is made with the internationally-patented Magnafolate® PRO, clinically tested as the world’s purest methylfolate (Magnafolate® PRO is shown to have significantly greater purity, stability and potency when compared to competing brands Quatrefolic® and Extrafolate®). Magnafolate® is made with a form of methylfolate called L-5-MTHF-Ca, which is shown to be the most active form of folate in the plasma circulation. When compared with ordinary folate, L-methylfolate was found to be absorbed faster and utilized more quickly in the body17.