THE PHARMACEUTICAL CODEX

THE PHARMACENTICAL CODEX
TWELFTH EDITION
This new edition has been completely revised and incorporates updated material as well as entirely fresh subject areas. The new Codex provides a reference source on all aspects of pharmaceutical science and technology that are relevant to the development and provision of medicines.
The practice of pharmacy has changed considerably in the last decade and pharmacists are increasingly called upon to provide information and advice. They need to be able to understand and explain to patients and other healthcare professionals the action, stability, handling, packaging, and storage of medicinal products. The Pharmaceutical Codex provides this knowledge of the scientific basis of pharmacy and of recent developments in pharmacy practice.
Part 1 covers the multidisciplinary nature of pharmaceutics and demonstrates how quality is built into medicines from conception and development to production and use. The chapters broadly encompass the pharmaceutics content of the syllabus for pharmacy undergraduates and also provide direction and support for the continuing education of graduates, with special emphasis on the requirements of those associated with product development and innovation. Part Il includes an extensive collection of pharmaceutical data, arranged in monograph form. The Codex is edited by staff of the Royal Pharmaceutical Society, using known experts to write individual chapters.
The Pharmaceutical Codex: Principles and Practice of Pharmaceutics represents an invaluable reference source to any person with an interest in the preparation and presentation of medicines including scientists engaged in formulation, development, or production; pre-registration pharmacy graduates; students of pharmacy and related subjects; and all pharmacists-both in the United Kingdom and overseas.
CONTENTS
Preface
PARTI. PREPARATION AND PRESENTATION OF DRUGS AS MEDICINES
Section 1. Dosage Forms: Oral solids. Oral liquids. Solution properties. Suspensions. Emulsions. Parenterals.
Aerosols. Inhalation products. Topical semi-solids. Topical liquids and powders. Ophthalmic products. Rectal and vaginal products
Section 2. Product Design, Development and Presentation: Preformulation. Formulation. Modified-release drug delivery systems. Biopharmaceutics & Pharmacokinetic principles. Rheology. Stability of medicinal products.
Incompatibility. Pharmaceutical packaging. Storage. Pharmaceutical aspects of clinical trials. Statistics.
Section 3. Preparation and Supply of Medicines: Good manufacturing practice. Licensing. Design criteria for production facilities. Process development. Validation. Dispensing procedures and practice-related guidelines. Weighing, measuring and counting. Infusion fluids: Admixtures and administration. Paediatric preparations. Radiopharmaceuticals. Cytotoxic drugs: Handling precautions. Medical gases. Immunological Section 4. Pharmaceutical Microbiology, Sterile Processing and Contamination Control: Pharmaceutical microbiology. Control of microbial contamination and the preservation of medicines. Pyrogens. Particulate contamination. Sterilization. Aseptic processing. Cleanrooms for pharmaceutical production. Disinfectants and antiseptics.
Section 5. Electrolyte Replacement, Nutrient Fluids and Dialysis Solutions: Electrolyte powders and oral rehydration solutions. Parenteral and enteral nutrition fluids. Peritoneal dialysis & haemodialysis preparations.
Section 6. Nomenclature and Miscellaneous Data: Nomenclature of organic compounds. Miscellaneous data.
PART II. MONOGRAPHS ON DRUG SUBSTANCES
The monographs describe the pharmaceutics related aspects of 154 active substances. In addition to relevant physiochemical data, the monographs include abstracts from key papers on topics that range across stability, storage, incompatibility, formulation, dosage form development, excipients, bioavailability & processing. Index