Melanofree 4% Cream

### **Melanofree 4% Cream**  
*A dermatologist-grade skin-lightening treatment formulated to target stubborn hyperpigmentation, melasma, and post-inflammatory marks with clinical efficacy.*  

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### **Active Mechanism**  
- **4% Niacinamide** – Inhibits melanin transfer to skin cells while strengthening the moisture barrier.  
- **Alpha-Arbutin 2%** – A gentle yet potent brightener that gradually fades dark spots without irritation.  
- **Hexylresorcinol 1%** – Disrupts melanin production pathways for enhanced lightening effects.  
- **Licorice Root Extract** – Natural anti-inflammatory that reduces redness and prevents rebound pigmentation.  

### **Clinical Applications**  
✓ Melasma (hormonal pigmentation)  
✓ Post-acne erythema (red/brown marks)  
✓ Sun-induced age spots  
✓ Off-label use for underarm/body hyperpigmentation  

### **Usage Protocol**  
1. **Patch test** behind ear for 24 hours before full application.  
2. Apply **pea-sized amount** to affected areas **once daily (PM)**.  
3. Gradually increase to **twice daily (AM/PM)** if tolerated after 2 weeks.  
4. **Mandatory SPF 50+** during daytime use.  

### **Texture & Tolerance**  
- **Featherlight emulsion** – Non-occlusive, suitable for face/body.  
- **Minimal side effects** – Less irritating than hydroquinone-based alternatives.  

### **Expected Outcomes**  
- **4-6 Weeks:** Visible lightening of superficial pigmentation.  
- **12-16 Weeks:** Significant improvement in stubborn melasma.  

⚠ **Critical Notes**  
- Not recommended during pregnancy/breastfeeding.  
- Avoid concomitant use with:  
 - Strong acids (AHA/BHA)  
 - Vitamin C (separate by 30 minutes if using)  

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### **Scientific Differentiation**  
Unlike hydroquinone creams, Melanofree:  
- Doesn’t cause ochronosis (blue-black discoloration)  
- Provides ancillary anti-aging benefits via collagen stimulation  

**Comparable Prescription Options:**  
- *Tri-Luma Cream (HQ 4% + Tretinoin)*  
- *Cosmelite 2 (HQ-free formula)*  

For **maintenance phase** after achieving results, switch to:  
-