Ostarine is a non-steroidal, orally available selective androgen receptor modulator (SARM) currently being studied for its potential to improve muscle mass, strength, and overall physical performance. Research has shown promising outcomes in both animal and human trials, particularly for preventing muscle loss, supporting bone health, and improving metabolic function.
Clinical studies have highlighted Ostarine’s ability to enhance lean body mass and strength without the typical side effects associated with traditional anabolic compounds. In one major double-blind, placebo-controlled trial involving older adults and postmenopausal women, Ostarine significantly increased lean muscle and improved physical performance, particularly in stair-climb power tests. Participants who received Ostarine also showed a decrease in fat mass and improved insulin sensitivity, with minimal hormonal disruption.
Another clinical trial involving individuals with muscle wasting conditions confirmed Ostarine’s potential to enhance muscle growth and physical function. Patients taking Ostarine at doses of 1–3 mg per day experienced measurable increases in lean body mass and stair-climb performance, while adverse events were mild and comparable to placebo. Notably, Ostarine demonstrated no negative impact on hair growth in women or prostate health in men.
The studies suggest that Ostarine may play an important role in maintaining muscle and metabolic health, especially for populations vulnerable to muscle deterioration due to aging, chronic illness, or inactivity. It has shown a favorable safety profile, with improvements in muscle, strength, and insulin response, making it a potential future therapeutic option for managing conditions such as sarcopenia, osteoporosis, and metabolic dysfunction.
**Key Clinical Findings:**
* Promotes lean muscle growth and enhances strength
* Supports physical performance and functional capacity
* Improves insulin sensitivity and reduces fat mass
* Exhibits a strong safety and tolerability profile