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DHEA is a potent steroid hormone that is naturally produced by the adrenal cortex. In certain circumstances, direct DHEA supplementation is recommended following appropriate diagnostic testing.
dhea
Dehydroepiandrosterone (DHEA) is one of the
hormones made in the human body by the adrenal
glands. DHEA circulates in the bloodstream as
DHEA-sulfate and is converted as needed into other
hormones. DHEA serves as the precursor to male
and female sex hormones (androgens and estro-
gens). DHEA levels are reported to be low in some
people with anorexia, end-stage kidney disease,
type 2 diabetes (non-insulin dependent diabetes),
adrenal insufficiency, and in the critically ill. DHEA
levels may also be depleted by a number of drugs,
including insulin, corticosteroids, opiates, and
danazol. Pure DHEA that has been micronized to
a very small particle size to facilitate absorption is
provided in these 10 mg vegetarian capsules.
FREQUENTLY ASKED QUESTIONS
What is DHEA?
DHEA is an abbreviation for dehydroepi-
androsterone, a hormone produced chiefly by the
adrenal glands. The testes, ovaries, and brain can
also make DHEA. As the most prevalent adrenal
steroid in the body, DHEA serves as a precursor to
the human sex steroid hormones, testosteronee and
estrogen.
How is DHEA produced in the body?
Cholesterol is the starting material used to make
all steroid hormones in the body. In the adrenal
glands, cholesterol is converted to pregnenolone
and pregnenolone is converted into DHEA and
a number of sex hormones including the female
hormones estrogen and progesteronee and the male
hormone testosteronee.
These statements have not been evaluated by the Food and Drug Administration. This product is
not intended to diagnose, treat, cure, or prevent any disease.
thewellnessway.com
Where does DHEA in supplements come from?
The starting source material for DHEA is a class
of plant hormones called sterols extracted from
wild yams that are grown commercially. The
most common plant sterol is diosgenin that has
a molecular structure very similar to DHEA. Di-
osgenin is converted to DHEA in the laboratory
by removing several side chains through various
chemical reactions.
Will natural yam extracts increase DHEA
levels?No. Although DHEA can be synthesized in
a laboratory using wild yam extract, conversion
of wild yam into DHEA by the body has not been
demonstrated. Products that claim wild yam to
be “natural DHEA” are inaccurate.
dhea
Will DHEA supplements suppress the body’s
nat ural DHEA production?
Although the production of most steroids in the
body is controlled by a feedback loop that limits
synthesis when hormone levels get too high, DHEA
appears to be an exception to this rule. Using
appropriate small, supplemental amounts of DHEA
will not stop the body’s natural DHEA production.
However, supplementation with high amounts of
DHEA for a long period may influence the body’s
natu ral DHEA production. Baseline blood levels
of DHEA should be evaluated prior to initiating
supplementation with DHEA.
How are levels of DHEA measured in the body?
To assess blood levels of DHEA, DHEA is often
measured in its sulfate form (DHEAS) because of
its greater stability. DHEAS is formed in the liver
by adding a sulfate (504) molecule to it. DHEAS
is cleared much more slowly by the kidneys, and
blood levels of this metabolite remain much more
stable throughout the day.
How much DHEA does the body make?
It is esti mated that humans produce between 1
and 2 mg of DHEA and 10 to 15 mg of DHEAS (the
sulfate metabolite) per day. Some researchers,
however, have estimated higher levels. DHEA levels
peak in early adulthood and then start a lifelong
descent.
These statements have not been evaluated by the Food and Drug Administration. This product is
not intended to diagnose, treat, cure, or prevent any disease.
thewellnessway.com
Are there any side effects to taking DHEA?
Few side effects are reported when DHEA
supplements are taken by mouth in
recommended doses. Because DHEA is a
hormone related to other male and female
hormones, there may be side effects related
to its hormonal activities. In women, there are
occasional reports of acne, facial hair, hair loss,
and increased sweating when taking more
than needed. Men may develop more breast
tenderness or increased aggressiveness. Use
of DHEA needs to be under the guidance of
a qualified healthcare professional who can
monitor its effects. DHEA is not recommended
during pregnancy or breastfeeding.
This product is free of the following common allergens: milk/casein,
eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, corn, yeast,
and soybeans. Con tains no artificial colors, flavors, or preservatives.
This product was made in a GMP and ISO 9001 :2008 registered
facility.
129943-DH1
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 100
Amount Per Capsule
DHEA (dehydroepiandrosterone, micronized) 10 mg*
(derived from wild yam)
*Daily Value not established.
DH1/200909.02
Other ingredients: Microcrystalline cellulose, vegetarian
capsule (hydroxypropyl methylcellulose, water), and
L-Leucine.
PLEASE ADD TO LEFT PANEL
Caution: Not for use by individuals under the age of 18
years. Do not use if pregnant or breastfeeding. Consult
a physician or licensed qualified healthcare professional
before using this product if you are a woman under the age
of 40; if you or someone in your family history has cancer,
prostate enlargement, high blood pressure or heart disease,
or low HDL (“good”) cholesterol; or if you are using any other
dietary supplement, prescription drug, or over-the-counter
drug. Do not exceed the recommended serving. Monitor
liver enzymes if usi
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