In 2009,
[4] five years after the events of
Resident Evil 4,
Chris Redfield, now an agent of the Bioterrorism Security Assessment Alliance (BSAA), is dispatched to Kijuju in Africa. He and his new partner
Sheva Alomar are tasked with apprehending Ricardo Irving before he can sell a bio-organic equipment (BOW) on the black market. When they arrive, they discover that the locals have been infected by the parasites Las Plagas (those infected are called "Majini") and the BSAA Alpha Team have been killed. Chris and Sheva are rescued by BSAA's Delta Team, which includes Sheva's mentor
Captain Josh Stone. In Stone's data Chris sees a photograph of
Jill Valentine, his old partner, who has been presumed dead after a confrontation with
Albert Wesker. Chris, Sheva and Delta Team close in on Irving, but he escapes with the aid of a hooded figure. Irving leaves documents that lead Chris and Sheva to marshy oilfields. This is where Irving's deal is to occur, but they discover that the documents are a diversion. When Chris and Sheva try to regroup with Delta Team, they find the team slaughtered by a BOW; Sheva cannot find Stone among the dead. Determined to learn if Valentine is still alive, Chris does not report to headquarters