PureBulk Fisetin 50% P.E. Powder 10grams

Product Details

What is Fisetin?

Fisetin is a botanical flavanol and provides yellow pigment for a variety of fruits and vegetables. Botanical antioxidants have garnered a lot of interest, as individuals can consume them for long stretches of time without experiencing negative effects. Fisetin is a potent antioxidant with senolytic effects, meaning it might improve longevity and lifelong health. It’s also a neuroprotector and anti-inflammatory agent. Animal and in vitro studies show great promise for fisetin, and several human clinical trials are underway.

Potential Fisetin Benefits

Longevity

Fisetin may be able to improve longevity and lifelong health by removing senescent cells. These cells stop dividing, which damages them and triggers the release of proinflammatory cytokines. Eliminating senescent cells can improve cell functioning, long-term health, and reduce inflammation. Fisetin kills these harmful cells while leaving healthy cells intact.

Antioxidant

Fisetin exerts antioxidant effects by scavenging free radicals and increasing the availability of other potent antioxidants. It also blocks the NF-kB signaling pathway. NF-kB proteins trigger the production of proinflammatory cytokines, chemokines, and adhesion molecules. It also prevents inflammatory enzymes from damaging fatty acids. Fisetin enhances cellular metabolism and improves longevity by removing metabolic waste from cells.

Cognition and Neuroprotection

Fisetin may improve memory and learning by activating long-term memory pathways in the brain. It also provides neuroprotection by blocking inflammatory molecules that target the brain’s innate immune system. Fisetin may help reduce plaque buildup in brain cells and preserve existing cells.

Other Fisetin Benefits

Fisetin supplements may support heart and liver health. Its antioxidant properties allow it to scavenge free radicals and reduce oxidative stress, both of which damage organ tissues. Fisetin may support strong bones too. It interferes with the activity of cells that weaken bones and may improve bone density.

Fisetin vs. Quercetin

Fisetin isn’t the only beneficial plant flavonoid. Resveratrol and quercetin are also botanic flavanols with powerful antioxidant properties. All three compounds are fat-soluble, and taking them with fats like fish oil may improve their bioavailability. One study comparing ten different flavonoids’ senolytic potential reported that fisetin was the most effective.

Supplement Facts & Directions

Supplement Facts

Serving Size: 300 milligrams
Servings Per Container: Varies

Amount Per Serving	% Daily Value*
Fisetin 150 mg (from 300 mg Cotinus Coggygria P.E.) (branch)	†

* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.

Other Ingredients: None

Free of: Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.

Directions: As a dietary supplement, take 300 mg (3/16 tsp) daily with a meal or glass of water, or as directed by a physician. Accurate gram weight scale recommended.