Resident Evil 5[a] is a third-person shooter video game developed and published by Capcom. It is a major installment in the Resident Evil series, and was announced in 2005—the same year its predecessor Resident Evil 4 was released. Resident Evil 5 was released for the PlayStation 3 and Xbox 360 consoles in March 2009 and for Microsoft Windows in September that year. The plot involves an investigation of a terrorist threat by Bioterrorism Security Assessment Alliance agents Chris Redfield and Sheva Alomar in Kijuju, a fictional region of Africa. Chris learns that he must confront his past in the form of an old enemy, Albert Wesker, and his former partner, Jill Valentine.

The gameplay of Resident Evil 5 is similar to that of the previous installment, though it is the first in the series designed for two-player cooperative gameplay. It has also been considered the first game in the main series to depart from the survival horror genre, with critics saying it bore more resemblance to an action game. Motion capture was used for the cutscenes, and it was the first video game to use a virtual camera system. Several staff members from the original Resident Evil worked on Resident Evil 5. The PC version was developed by Mercenary Technology.